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Activation of a Novel Calcineurin-mediated Insulin-like Growth Factor-1 Receptor Pathway, Altered Metabolism, and Tumor Cell Invasion in Cells Subjected to Mitochondrial Respiratory Stress

We have previously shown that disruption of mitochondrial membrane potential by depletion of mitochondrial DNA (mtDNA) or treatment with a mitochondrial ionophore, carbonyl cyanide m-chlorophenylhydrazone, initiates a stress signaling, which causes resistance to apoptosis, and induces invasive behav...

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Bibliografische gegevens
Hoofdauteurs: Guha, Manti, Srinivasan, Satish, Biswas, Gopa, Avadhani, Narayan G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800738/
https://ncbi.nlm.nih.gov/pubmed/17355970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M611693200
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