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Activation of a Novel Calcineurin-mediated Insulin-like Growth Factor-1 Receptor Pathway, Altered Metabolism, and Tumor Cell Invasion in Cells Subjected to Mitochondrial Respiratory Stress

We have previously shown that disruption of mitochondrial membrane potential by depletion of mitochondrial DNA (mtDNA) or treatment with a mitochondrial ionophore, carbonyl cyanide m-chlorophenylhydrazone, initiates a stress signaling, which causes resistance to apoptosis, and induces invasive behav...

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Main Authors: Guha, Manti, Srinivasan, Satish, Biswas, Gopa, Avadhani, Narayan G.
格式: Artigo
語言:Inglês
出版: 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800738/
https://ncbi.nlm.nih.gov/pubmed/17355970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M611693200
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