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Mitochondrial respiratory defects promote the Warburg effect and cancer progression

In the past decade mitochondria have emerged as an important cellular signaling hub controlling metabolism, epigenetics, and cell fate. Dysfunctional mitochondria initiate a retrograde nuclear response that influences the cellular reprograming observed in various human pathologies, including cancer....

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發表在:Mol Cell Oncol
Main Authors: Srinivasan, Satish, Guha, Manti, Avadhani, Narayan G.
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905388/
https://ncbi.nlm.nih.gov/pubmed/27308608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1085120
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