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Mitochondrial genome and functional defects in osteosarcoma are associated with their aggressive phenotype

Osteosarcoma (OSA) is an aggressive mesenchymal tumor of the bone that affects children and occurs spontaneously in dogs. Human and canine OSA share similar clinical, biological and genetic features, which make dogs an excellent comparative model to investigate the etiology and pathogenesis of OSA....

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Jackson, Martina, Serada, Nicole, Sheehan, Maura, Srinivasan, Satish, Mason, Nicola, Guha, Manti, Avadhani, Narayan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6303035/
https://ncbi.nlm.nih.gov/pubmed/30576337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209489
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