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Mitochondrial genome and functional defects in osteosarcoma are associated with their aggressive phenotype

Osteosarcoma (OSA) is an aggressive mesenchymal tumor of the bone that affects children and occurs spontaneously in dogs. Human and canine OSA share similar clinical, biological and genetic features, which make dogs an excellent comparative model to investigate the etiology and pathogenesis of OSA....

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jackson, Martina, Serada, Nicole, Sheehan, Maura, Srinivasan, Satish, Mason, Nicola, Guha, Manti, Avadhani, Narayan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6303035/
https://ncbi.nlm.nih.gov/pubmed/30576337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209489
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