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Defects in cytochrome c oxidase expression induce a metabolic shift to glycolysis and carcinogenesis
Mitochondrial metabolic dysfunction is often seen in cancers. This paper shows that the defect in a mitochondrial electron transport component, the cytochrome c oxidase (CcO), leads to increased glycolysis and carcinogenesis. Using whole genome microarray expression analysis we show that genetic sil...
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| Publicado no: | Genom Data |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4664720/ https://ncbi.nlm.nih.gov/pubmed/26697345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gdata.2015.07.031 |
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