Aggressive triple negative breast cancers have unique molecular signature on the basis of mitochondrial genetic and functional defects

Metastatic breast cancer is a leading cause of cancer-related deaths in women worldwide. Patients with triple negative breast cancer (TNBCs), a highly aggressive tumor subtype, have a particularly poor prognosis. Multiple reports demonstrate that altered content of the multicopy mitochondrial genome...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta Mol Basis Dis
Main Authors: Guha, Manti, Srinivasan, Satish, Raman, Pichai, Jiang, Yuefu, Kaufman, Brett A., Taylor, Deanne, Dong, Dawei, Chakrabarti, Rumela, Picard, Martin, Carstens, Russ P., Kijima, Yuko, Feldman, Mike, Avadhani, Narayan G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6417497/
https://ncbi.nlm.nih.gov/pubmed/29309924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2018.01.002
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