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Activation of a Novel Calcineurin-mediated Insulin-like Growth Factor-1 Receptor Pathway, Altered Metabolism, and Tumor Cell Invasion in Cells Subjected to Mitochondrial Respiratory Stress

We have previously shown that disruption of mitochondrial membrane potential by depletion of mitochondrial DNA (mtDNA) or treatment with a mitochondrial ionophore, carbonyl cyanide m-chlorophenylhydrazone, initiates a stress signaling, which causes resistance to apoptosis, and induces invasive behav...

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Bibliografske podrobnosti
Main Authors: Guha, Manti, Srinivasan, Satish, Biswas, Gopa, Avadhani, Narayan G.
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800738/
https://ncbi.nlm.nih.gov/pubmed/17355970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M611693200
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