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Mitochondria-to-nucleus stress signaling in mammalian cells: Nature of nuclear gene targets, transcription regulation, and induced resistance to apoptosis

Depletion of mitochondrial DNA (mtDNA) or treatment with mitochondrial poison CCCP initiates mitochondrial stress signaling, which operates through altered Ca(2+) homeostasis. In C2C12 rhabdomyoblasts and A549 human lung carcinoma cells mitochondrial stress signaling activates calcineurin and a numb...

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Bibliografiset tiedot
Päätekijät: Biswas, Gopa, Guha, Manti, Avadhani, Narayan G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2005
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800739/
https://ncbi.nlm.nih.gov/pubmed/15978749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2005.03.028
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