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Dioxin-mediated tumor progression through activation of mitochondria-to-nucleus stress signaling
The environmental toxin 2,3,7,8-tetrachlorodibenzodioxin (TCDD) is a known human carcinogen; however, its precise mechanism of action remains unclear. Here we show that TCDD induces mitochondrial dysfunction, stress signaling, and tumor invasion by a mechanism similar to that described for mtDNA-dep...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2224183/ https://ncbi.nlm.nih.gov/pubmed/18172213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706183104 |
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