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Minute-scale persistence of a GPCR conformation state triggered by non-cognate G protein interactions primes signaling
Despite the crowded nature of the cellular milieu, ligand–GPCR–G protein interactions are traditionally viewed as spatially and temporally isolated events. In contrast, recent reports suggest the spatial and temporal coupling of receptor–effector interactions, with the potential to diversify downstr...
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| Pubblicato in: | Nat Commun |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6811539/ https://ncbi.nlm.nih.gov/pubmed/31645561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12755-9 |
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