3195 Genomic Analysis of Primary Plasma Cell Leukemia reveals Complex Cytogenetic Alterations and High Risk Mutational Patterns

OBJECTIVES/SPECIFIC AIMS: 1) Determine the mutational landscape, including translocation, mutations and mutational signatures as well as copy number variations of pPCL and identify significant differences to non pPCL MM. 2) Determine whether genetic changes pertinent to pPCL could be explored as the...

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Bibliographic Details
Published in:J Clin Transl Sci
Main Authors: Schinke, Carolina, Boyle, Eileen, Ashby, Cody, Wang, Yan, Christopher Wardell, Davies, Thanendrarajan, Sharmilan, Zangari, maurizio, van Rhee, Frits, Morgan, Gareth, Walker, Brian
Format: Artigo
Language:Inglês
Published: Cambridge University Press 2019
Subjects:
Basic/Translational Science/Team Science
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6799478/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2019.31
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