3195 Genomic Analysis of Primary Plasma Cell Leukemia reveals Complex Cytogenetic Alterations and High Risk Mutational Patterns

OBJECTIVES/SPECIFIC AIMS: 1) Determine the mutational landscape, including translocation, mutations and mutational signatures as well as copy number variations of pPCL and identify significant differences to non pPCL MM. 2) Determine whether genetic changes pertinent to pPCL could be explored as the...

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Bibliografske podrobnosti
izdano v:J Clin Transl Sci
Main Authors: Schinke, Carolina, Boyle, Eileen, Ashby, Cody, Wang, Yan, Christopher Wardell, Davies, Thanendrarajan, Sharmilan, Zangari, maurizio, van Rhee, Frits, Morgan, Gareth, Walker, Brian
Format: Artigo
Jezik:Inglês
Izdano: Cambridge University Press 2019
Teme:
Basic/Translational Science/Team Science
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6799478/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2019.31
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