The functional epigenetic landscape of aberrant gene expression in molecular subgroups of newly diagnosed multiple myeloma

BACKGROUND: Multiple Myeloma (MM) is a hematological malignancy with genomic heterogeneity and poor survival outcome. Apart from the central role of genetic lesions, epigenetic anomalies have been identified as drivers in the development of the disease. METHODS: Alterations in the DNA methylome were...

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Dettagli Bibliografici
Pubblicato in:J Hematol Oncol
Autori principali: Choudhury, Samrat Roy, Ashby, Cody, Tytarenko, Ruslana, Bauer, Michael, Wang, Yan, Deshpande, Shayu, Den, Judith, Schinke, Carolina, Zangari, Maurizio, Thanendrarajan, Sharmilan, Davies, Faith E., van Rhee, Frits, Morgan, Gareth J., Walker, Brian A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7409490/
https://ncbi.nlm.nih.gov/pubmed/32762714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-020-00933-y
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