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Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma
To elucidate the mechanisms underlying relapse from chemotherapy in multiple myeloma, we performed a longitudinal study of 33 patients entered into Total Therapy protocols investigating them using gene expression profiling, high-resolution copy number arrays, and whole-exome sequencing. The study il...
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| Publicado no: | Blood |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5043128/ https://ncbi.nlm.nih.gov/pubmed/27516441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-06-723007 |
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