Kinase domain activation through gene rearrangement in multiple myeloma

Chromosomal rearrangements that result in oncogenic kinase activation are present in many solid and hematological malignancies, but none have been reported in multiple myeloma (MM). Here we analyzed 1421 samples from 958 myeloma patients using a targeted assay and detected fusion genes in 1.5% of pa...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Leukemia
Glavni autori: Morgan, Gareth J, He, Jie, Tytarenko, Ruslana, Patel, Purvi, Stephens, Owen W, Zhong, Shan, Deshpande, Shayu, Bauer, Michael, Weinhold, Niels, Schinke, Carolina, Rasche, Leo, Bailey, Mark, Ali, Siraj, Ross, Jeff, Miller, Vincent A, Stephens, Phillip, Thanendrarajan, Sharmilan, Zangari, Maurizio, van Rhee, Frits, Mughal, Tariq, Davies, Faith E, Walker, Brian A
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224403/
https://ncbi.nlm.nih.gov/pubmed/29654269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-018-0108-y
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items