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Kinase domain activation through gene rearrangement in multiple myeloma
Chromosomal rearrangements that result in oncogenic kinase activation are present in many solid and hematological malignancies, but none have been reported in multiple myeloma (MM). Here we analyzed 1421 samples from 958 myeloma patients using a targeted assay and detected fusion genes in 1.5% of pa...
Kaydedildi:
| Yayımlandı: | Leukemia |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group UK
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6224403/ https://ncbi.nlm.nih.gov/pubmed/29654269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-018-0108-y |
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