3195 Genomic Analysis of Primary Plasma Cell Leukemia reveals Complex Cytogenetic Alterations and High Risk Mutational Patterns

OBJECTIVES/SPECIFIC AIMS: 1) Determine the mutational landscape, including translocation, mutations and mutational signatures as well as copy number variations of pPCL and identify significant differences to non pPCL MM. 2) Determine whether genetic changes pertinent to pPCL could be explored as the...

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Detalhes bibliográficos
Publicado no:J Clin Transl Sci
Main Authors: Schinke, Carolina, Boyle, Eileen, Ashby, Cody, Wang, Yan, Christopher Wardell, Davies, Thanendrarajan, Sharmilan, Zangari, maurizio, van Rhee, Frits, Morgan, Gareth, Walker, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: Cambridge University Press 2019
Assuntos:
Basic/Translational Science/Team Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6799478/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2019.31
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