Linked dual-class HIV resistance mutations are associated with treatment failure

We hypothesized that HIV-1 with dual-class but not single-class drug resistance mutations linked on the same viral genome, present in the virus population before initiation of antiretroviral therapy (ART), would be associated with failure of ART to suppress viremia. To test this hypothesis, we utili...

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Опубликовано в: :JCI Insight
Главные авторы: Boltz, Valerie F., Shao, Wei, Bale, Michael J., Halvas, Elias K., Luke, Brian, McIntyre, James A., Schooley, Robert T., Lockman, Shahin, Currier, Judith S., Sawe, Fred, Hogg, Evelyn, Hughes, Michael D., Kearney, Mary F., Coffin, John M., Mellors, John W.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2019
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795402/
https://ncbi.nlm.nih.gov/pubmed/31487271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.130118
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