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Rab5 Mediates an Amyloid Precursor Protein Signaling Pathway That Leads to Apoptosis
Alzheimer's disease (AD) involves activation of apoptotic pathways that may be regulated through signaling cascades initiated by the amyloid precursor protein (APP). Enlarged endosomes have been observed in postmortem AD brains at very early stages of the disease. We show here that exogenous ex...
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| Yayımlandı: | J Neurosci |
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| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Society for Neuroscience
2007
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6794581/ https://ncbi.nlm.nih.gov/pubmed/17611268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4599-06.2007 |
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