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Overexpression in Neurons of Human Presenilin-1 or a Presenilin-1 Familial Alzheimer Disease Mutant Does Not Enhance Apoptosis
Programmed cell death, or apoptosis, has been implicated in Alzheimer’s disease (AD). DNA damage was assessed in primary cortical neurons infected with herpes simplex virus (HSV) vectors expressing the familial Alzheimer’s disease (FAD) gene presenilin-1 (PS-1) or an FAD mutant of this gene, A246E....
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| Vydáno v: | J Neurosci |
|---|---|
| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Society for Neuroscience
1998
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6793279/ https://ncbi.nlm.nih.gov/pubmed/9822738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-23-09790.1998 |
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