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Dysfunction of Amyloid Precursor Protein Signaling in Neurons Leads to DNA Synthesis and Apoptosis

The classic neuropathological diagnostic markers for AD are amyloid plaques and neurofibrillary tangles, but their role in the etiology and progression of the disease remains incompletely defined. Research over the last decade has revealed that cell cycle abnormalities also represent a major neuropa...

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Detalhes bibliográficos
Main Authors: Neve, Rachael L., McPhie, Donna L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1862818/
https://ncbi.nlm.nih.gov/pubmed/17113271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2006.10.008
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