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Dysfunction of Amyloid Precursor Protein Signaling in Neurons Leads to DNA Synthesis and Apoptosis
The classic neuropathological diagnostic markers for AD are amyloid plaques and neurofibrillary tangles, but their role in the etiology and progression of the disease remains incompletely defined. Research over the last decade has revealed that cell cycle abnormalities also represent a major neuropa...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1862818/ https://ncbi.nlm.nih.gov/pubmed/17113271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2006.10.008 |
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