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Dysfunction of Amyloid Precursor Protein Signaling in Neurons Leads to DNA Synthesis and Apoptosis

The classic neuropathological diagnostic markers for AD are amyloid plaques and neurofibrillary tangles, but their role in the etiology and progression of the disease remains incompletely defined. Research over the last decade has revealed that cell cycle abnormalities also represent a major neuropa...

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Bibliografiske detaljer
Main Authors: Neve, Rachael L., McPhie, Donna L.
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1862818/
https://ncbi.nlm.nih.gov/pubmed/17113271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2006.10.008
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