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Age-Dependent Neuronal and Synaptic Degeneration in Mice Transgenic for the C Terminus of the Amyloid Precursor Protein

The molecular basis for the degeneration of neurons and the deposition of amyloid in plaques and in the cerebrovasculature in Alzheimer’s disease (AD) is incompletely understood. We have proposed that one molecule common to these abnormal processes is a fragment of the Alzheimer amyloid precursor pr...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Oster-Granite, Mary Lou, McPhie, Donna L., Greenan, Jane, Neve, Rachael L.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579256/
https://ncbi.nlm.nih.gov/pubmed/8824314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.16-21-06732.1996
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