TIN2 Functions with TPP1/POT1 To Stimulate Telomerase Processivity

TIN2 is an important regulator of telomere length, and mutations in TINF2, the gene encoding TIN2, cause short-telomere syndromes. While the genetics underscore the importance of TIN2, the mechanism through which TIN2 regulates telomere length remains unclear. Here, we tested the effects of human TI...

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Udgivet i:Mol Cell Biol
Main Authors: Pike, Alexandra M., Strong, Margaret A., Ouyang, John Paul T., Greider, Carol W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791651/
https://ncbi.nlm.nih.gov/pubmed/31383750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00593-18
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