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TIN2-Tethered TPP1 Recruits Human Telomerase to Telomeres In Vivo

Recruitment to telomeres is a pivotal step in the function and regulation of human telomerase; however, the molecular basis for recruitment is not known. Here, we have directly investigated the process of telomerase recruitment via fluorescence in situ hybridization (FISH) and chromatin immunoprecip...

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Bibliographische Detailangaben
Hauptverfasser: Abreu, Eladio, Aritonovska, Elena, Reichenbach, Patrick, Cristofari, Gaël, Culp, Brad, Terns, Rebecca M., Lingner, Joachim, Terns, Michael P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876666/
https://ncbi.nlm.nih.gov/pubmed/20404094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00240-10
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