The Shelterin TIN2 Subunit Mediates Recruitment of Telomerase to Telomeres

Dyskeratosis Congenita (DC) is a heritable multi-system disorder caused by abnormally short telomeres. Clinically diagnosed by the mucocutaneous symptoms, DC patients are at high risk for bone marrow failure, pulmonary fibrosis, and multiple types of cancers. We have recapitulated the most common DC...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS Genet
Main Authors: Frank, Amanda K., Tran, Duy C., Qu, Roy W., Stohr, Bradley A., Segal, David J., Xu, Lifeng
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521702/
https://ncbi.nlm.nih.gov/pubmed/26230315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005410
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