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The Shelterin TIN2 Subunit Mediates Recruitment of Telomerase to Telomeres

Dyskeratosis Congenita (DC) is a heritable multi-system disorder caused by abnormally short telomeres. Clinically diagnosed by the mucocutaneous symptoms, DC patients are at high risk for bone marrow failure, pulmonary fibrosis, and multiple types of cancers. We have recapitulated the most common DC...

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Detaylı Bibliyografya
Yayımlandı:PLoS Genet
Asıl Yazarlar: Frank, Amanda K., Tran, Duy C., Qu, Roy W., Stohr, Bradley A., Segal, David J., Xu, Lifeng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521702/
https://ncbi.nlm.nih.gov/pubmed/26230315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005410
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