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The Shelterin TIN2 Subunit Mediates Recruitment of Telomerase to Telomeres

Dyskeratosis Congenita (DC) is a heritable multi-system disorder caused by abnormally short telomeres. Clinically diagnosed by the mucocutaneous symptoms, DC patients are at high risk for bone marrow failure, pulmonary fibrosis, and multiple types of cancers. We have recapitulated the most common DC...

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Dades bibliogràfiques
Publicat a:PLoS Genet
Autors principals: Frank, Amanda K., Tran, Duy C., Qu, Roy W., Stohr, Bradley A., Segal, David J., Xu, Lifeng
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521702/
https://ncbi.nlm.nih.gov/pubmed/26230315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005410
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