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POT1–TPP1 enhances telomerase processivity by slowing primer dissociation and aiding translocation

Telomerase contributes to chromosome end replication by synthesizing repeats of telomeric DNA, and the telomeric DNA-binding proteins protection of telomeres (POT1) and TPP1 synergistically increase its repeat addition processivity. To understand the mechanism of increased processivity, we measured...

詳細記述

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書誌詳細
主要な著者: Latrick, Chrysa M, Cech, Thomas R
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837173/
https://ncbi.nlm.nih.gov/pubmed/20094033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.409
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