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Catalytic Enantio- and Diastereoselective Cyclopropanation of 2-Azadienes for the Synthesis of Aminocyclopropanes Bearing Quaternary Carbon Stereogenic Centers

We report the catalytic enantio- and diastereoselective preparation of aminocyclopropanes by the cyclopropanation of terminal and (Z)-internal 2-azadienes with donor/acceptor carbenes derived from α-diazoesters. The resulting cyclopropanes bear quaternary carbon stereogenic centers vicinal to the am...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Shao, Xinxin, Malcolmson, Steven J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6790987/
https://ncbi.nlm.nih.gov/pubmed/31465235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.9b02692
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