Autocatalytic amplification of Alzheimer-associated Aβ42 peptide aggregation in human cerebrospinal fluid

Alzheimer’s disease is linked to amyloid β (Aβ) peptide aggregation in the brain, and a detailed understanding of the molecular mechanism of Aβ aggregation may lead to improved diagnostics and therapeutics. While previous studies have been performed in pure buffer, we approach the mechanism in vivo...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Commun Biol
Auteurs principaux: Frankel, Rebecca, Törnquist, Mattias, Meisl, Georg, Hansson, Oskar, Andreasson, Ulf, Zetterberg, Henrik, Blennow, Kaj, Frohm, Birgitta, Cedervall, Tommy, Knowles, Tuomas P. J., Leiding, Thom, Linse, Sara
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783456/
https://ncbi.nlm.nih.gov/pubmed/31602414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0612-2
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires