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Co-temporal Force and Fluorescence Measurements Reveal a Ribosomal Gear-shift Mechanism of Translation Regulation by mRNA Secondary Structures
Movement of ribosomes on mRNA is often interrupted by secondary structures that present mechanical barriers and play a central role in translation regulation. We investigate how ribosomes couple their internal conformational changes with the activity of translocation factor EF-G to unwind mRNA secon...
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| Yayımlandı: | Mol Cell |
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| Asıl Yazarlar: | , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6779417/ https://ncbi.nlm.nih.gov/pubmed/31471187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.07.024 |
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