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The Ribosome Uses Two Active Mechanisms to Unwind mRNA During Translation

The ribosome translates the genetic information encoded in messenger RNA into protein. Folded structures in the coding region of an mRNA represent a kinetic barrier that slows the peptide elongation rate, as the ribosome must disrupt structures it encounters in the mRNA at its entry site to enable t...

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Autors principals: Qu, Xiaohui, Wen, Jin-Der, Lancaster, Laura, Noller, Harry F., Bustamante, Carlos, Tinoco, Ignacio
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170678/
https://ncbi.nlm.nih.gov/pubmed/21734708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10126
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