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Following translation by single ribosomes one codon at a time
We have followed individual ribosomes as they translate single messenger RNA hairpins tethered by the ends to optical tweezers. Here we reveal that translation occurs through successive translocation-and-pause cycles. The distribution of pause lengths, with a median of 2.8 s, indicates that at least...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2556548/ https://ncbi.nlm.nih.gov/pubmed/18327250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06716 |
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