Direct measurement of the mechanical work during translocation by the ribosome

A detailed understanding of tRNA/mRNA translocation requires measurement of the forces generated by the ribosome during this movement. Such measurements have so far remained elusive and, thus, little is known about the relation between force and translocation and how this reflects on its mechanism a...

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Bibliographic Details
Main Authors: Liu, Tingting, Kaplan, Ariel, Alexander, Lisa, Yan, Shannon, Wen, Jin-Der, Lancaster, Laura, Wickersham, Charles E, Fredrick, Kurt, Noller, Harry, Tinoco, Ignacio, Bustamante, Carlos J
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2014
Subjects:
Biochemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126342/
https://ncbi.nlm.nih.gov/pubmed/25114092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03406
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