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Impaired ligand‐dependent MET activation caused by an extracellular SEMA domain missense mutation in lung cancer
Aberrant activation of the MET/hepatocyte growth factor (HGF) receptor participates in the malignant behavior of cancer cells, such as invasion‐metastasis and resistance to molecular targeted drugs. Many mutations in the MET extracellular region have been reported, but their significance is largely...
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| Pubblicato in: | Cancer Sci |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6778621/ https://ncbi.nlm.nih.gov/pubmed/31342590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14142 |
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