Impaired ligand‐dependent MET activation caused by an extracellular SEMA domain missense mutation in lung cancer

Aberrant activation of the MET/hepatocyte growth factor (HGF) receptor participates in the malignant behavior of cancer cells, such as invasion‐metastasis and resistance to molecular targeted drugs. Many mutations in the MET extracellular region have been reported, but their significance is largely...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cancer Sci
Auteurs principaux: Miao, Wenyu, Sakai, Katsuya, Sato, Hiroki, Imamura, Ryu, Jangphattananont, Nawaphat, Takagi, Junichi, Nishita, Michiru, Minami, Yasuhiro, Matsumoto, Kunio
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778621/
https://ncbi.nlm.nih.gov/pubmed/31342590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14142
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