Impaired ligand‐dependent MET activation caused by an extracellular SEMA domain missense mutation in lung cancer

Aberrant activation of the MET/hepatocyte growth factor (HGF) receptor participates in the malignant behavior of cancer cells, such as invasion‐metastasis and resistance to molecular targeted drugs. Many mutations in the MET extracellular region have been reported, but their significance is largely...

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Bibliografiske detaljer
Udgivet i:Cancer Sci
Main Authors: Miao, Wenyu, Sakai, Katsuya, Sato, Hiroki, Imamura, Ryu, Jangphattananont, Nawaphat, Takagi, Junichi, Nishita, Michiru, Minami, Yasuhiro, Matsumoto, Kunio
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778621/
https://ncbi.nlm.nih.gov/pubmed/31342590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14142
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