Distinct Localization of Mature HGF from its Precursor Form in Developing and Repairing the Stomach

Hepatocyte growth factor (HGF) is secreted as an inactive single-chain HGF (scHGF); however, only proteolytically processed two-chain HGF (tcHGF) can activate the MET receptor. We investigated the localization of tcHGF and activated/phosphorylated MET (pMET) using a tcHGF-specific antibody. In day 1...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Jangphattananont, Nawaphat, Sato, Hiroki, Imamura, Ryu, Sakai, Katsuya, Terakado, Yumi, Murakami, Kazuhiro, Barker, Nick, Oshima, Hiroko, Oshima, Masanobu, Takagi, Junichi, Kato, Yukinari, Yano, Seiji, Matsumoto, Kunio
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628191/
https://ncbi.nlm.nih.gov/pubmed/31212972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20122955
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