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Impaired ligand‐dependent MET activation caused by an extracellular SEMA domain missense mutation in lung cancer
Aberrant activation of the MET/hepatocyte growth factor (HGF) receptor participates in the malignant behavior of cancer cells, such as invasion‐metastasis and resistance to molecular targeted drugs. Many mutations in the MET extracellular region have been reported, but their significance is largely...
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| Publicado no: | Cancer Sci |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6778621/ https://ncbi.nlm.nih.gov/pubmed/31342590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14142 |
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