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Impaired ligand‐dependent MET activation caused by an extracellular SEMA domain missense mutation in lung cancer

Aberrant activation of the MET/hepatocyte growth factor (HGF) receptor participates in the malignant behavior of cancer cells, such as invasion‐metastasis and resistance to molecular targeted drugs. Many mutations in the MET extracellular region have been reported, but their significance is largely...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cancer Sci
Päätekijät: Miao, Wenyu, Sakai, Katsuya, Sato, Hiroki, Imamura, Ryu, Jangphattananont, Nawaphat, Takagi, Junichi, Nishita, Michiru, Minami, Yasuhiro, Matsumoto, Kunio
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778621/
https://ncbi.nlm.nih.gov/pubmed/31342590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14142
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