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The ATP-powered gymnastics of TRiC/CCT: an asymmetric protein folding machine with a symmetric origin story
The eukaryotic chaperonin TRiC/CCT is a large hetero-oligomeric complex that plays an essential role assisting cellular protein folding and suppressing protein aggregation. It consists of two rings, each composed of eight different subunits; non-native polypeptides bind and fold in an ATP-dependent...
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| Pubblicato in: | Curr Opin Struct Biol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6776438/ https://ncbi.nlm.nih.gov/pubmed/30978594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2019.03.002 |
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