The molecular architecture of the eukaryotic chaperonin TRiC/CCT

TRiC/CCT is a highly conserved and essential chaperonin that uses ATP cycling to facilitate folding of approximately 10% of the eukaryotic proteome. This 1 MDa hetero-oligomeric complex consists of two stacked rings of eight paralogous subunits each. Previously proposed TRiC models differ substantia...

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Autori principali: Leitner, Alexander, Joachimiak, Lukasz A., Bracher, Andreas, Mönkemeyer, Leonie, Walzthoeni, Thomas, Chen, Bryan, Pechmann, Sebastian, Holmes, Susan, Cong, Yao, Ma, Boxue, Ludtke, Steve, Chiu, Wah, Hartl, F. Ulrich, Aebersold, Ruedi, Frydman, Judith
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350567/
https://ncbi.nlm.nih.gov/pubmed/22503819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.03.007
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