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The structural basis of substrate recognition by the eukaryotic chaperonin TRiC/CCT

The eukaryotic chaperonin TRiC (also called CCT) is the obligate chaperone for many essential proteins. TRiC is hetero-oligomeric, comprising two stacked rings of eight different subunits each. Subunit diversification from simpler archaeal chaperonins appears linked to proteome expansion. Here, we i...

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Détails bibliographiques
Publié dans:Cell
Auteurs principaux: Joachimiak, Lukasz A., Walzthoeni, Thomas, Liu, Corey, Aebersold, Ruedi, Frydman, Judith
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298165/
https://ncbi.nlm.nih.gov/pubmed/25416944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.10.042
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