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The structural basis of substrate recognition by the eukaryotic chaperonin TRiC/CCT
The eukaryotic chaperonin TRiC (also called CCT) is the obligate chaperone for many essential proteins. TRiC is hetero-oligomeric, comprising two stacked rings of eight different subunits each. Subunit diversification from simpler archaeal chaperonins appears linked to proteome expansion. Here, we i...
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| Veröffentlicht in: | Cell |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4298165/ https://ncbi.nlm.nih.gov/pubmed/25416944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.10.042 |
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