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Folding of large multidomain proteins by partial encapsulation in the chaperonin TRiC/CCT
The eukaryotic chaperonin, TRiC/CCT (TRiC, TCP-1 ring complex; CCT, chaperonin containing TCP-1), uses a built-in lid to mediate protein folding in an enclosed central cavity. Recent structural data suggest an effective size limit for the TRiC folding chamber of ∼70 kDa, but numerous chaperonin subs...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3535605/ https://ncbi.nlm.nih.gov/pubmed/23197838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218836109 |
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