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Modulation of STAT3 Folding and Function by TRiC/CCT Chaperonin

Signal transducer and activator of transcription 3 (Stat3) transduces signals of many peptide hormones from the cell surface to the nucleus and functions as an oncoprotein in many types of cancers, yet little is known about how it achieves its native folded state within the cell. Here we show that S...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kasembeli, Moses, Lau, Wilson Chun Yu, Roh, Soung-Hun, Eckols, T. Kris, Frydman, Judith, Chiu, Wah, Tweardy, David J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995649/
https://ncbi.nlm.nih.gov/pubmed/24756126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001844
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