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The ATP-powered gymnastics of TRiC/CCT: an asymmetric protein folding machine with a symmetric origin story

The eukaryotic chaperonin TRiC/CCT is a large hetero-oligomeric complex that plays an essential role assisting cellular protein folding and suppressing protein aggregation. It consists of two rings, each composed of eight different subunits; non-native polypeptides bind and fold in an ATP-dependent...

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Detalhes bibliográficos
Publicado no:Curr Opin Struct Biol
Main Authors: Gestaut, Dan, Limatola, Antonio, Joachimiak, Lukasz, Frydman, Judith
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776438/
https://ncbi.nlm.nih.gov/pubmed/30978594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2019.03.002
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