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Therapeutic targeting of 3’,5’-cyclic nucleotide phosphodiesterases: Inhibition and beyond
Phosphodiesterases (PDEs), enzymes that degrade 3’,5’-cyclic nucleotides, are being pursued as therapeutic targets for several diseases, including those affecting the nervous system, cardiovascular system, fertility, immunity, cancer, and metabolism. Clinical development programmes have focused excl...
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| Publicado no: | Nat Rev Drug Discov |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6773486/ https://ncbi.nlm.nih.gov/pubmed/31388135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41573-019-0033-4 |
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