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Therapeutic targeting of 3’,5’-cyclic nucleotide phosphodiesterases: Inhibition and beyond
Phosphodiesterases (PDEs), enzymes that degrade 3’,5’-cyclic nucleotides, are being pursued as therapeutic targets for several diseases, including those affecting the nervous system, cardiovascular system, fertility, immunity, cancer, and metabolism. Clinical development programmes have focused excl...
Shranjeno v:
| izdano v: | Nat Rev Drug Discov |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6773486/ https://ncbi.nlm.nih.gov/pubmed/31388135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41573-019-0033-4 |
| Oznake: |
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