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Advances in targeting cyclic nucleotide phosphodiesterases
Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolysis of cyclic AMP and cyclic GMP, thereby regulating the intracellular concentrations of these cyclic nucleotides, their signalling pathways and, consequently, myriad biological responses in health and disease. Currently, a small number...
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| Main Authors: | , , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4155750/ https://ncbi.nlm.nih.gov/pubmed/24687066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd4228 |
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