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Insulin-induced formation of macromolecular complexes involved in activation of cyclic nucleotide phosphodiesterase 3B (PDE3B) and its interaction with PKB

Fractionation of 3T3-L1 adipocyte membranes revealed that PDE3B (phosphodiesterase 3B) was associated with PM (plasma membrane) and ER (endoplasmic reticulum)/Golgi fractions, that insulin-induced phosphorylation/activation of PDE3B was greater in internal membranes than PM fractions, and that there...

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Autors principals: Ahmad, Faiyaz, Lindh, Rebecka, Tang, Yan, Weston, Marie, Degerman, Eva, Manganiello, Vincent C.
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868803/
https://ncbi.nlm.nih.gov/pubmed/17324123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060960
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