Selective regulation of cyclic nucleotide phosphodiesterase PDE3A isoforms

Inhibitors of cyclic nucleotide phosphodiesterase (PDE) PDE3A have inotropic actions in human myocardium, but their long-term use increases mortality in patients with heart failure. Two isoforms in cardiac myocytes, PDE3A1 and PDE3A2, have identical amino acid sequences except for a unique N-termina...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Vandeput, Fabrice, Szabo-Fresnais, Nicolas, Ahmad, Faiyaz, Kho, Changwon, Lee, Ahyoung, Krall, Judith, Dunlop, Allan, Hazel, Mark W., Wohlschlegel, James A., Hajjar, Roger J., Houslay, Miles D., Manganiello, Vincent C., Movsesian, Matthew A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856833/
https://ncbi.nlm.nih.gov/pubmed/24248367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1305427110
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados